When dehydration conditions persist in the body for a very long time, it can affect the vital organs and lead to chronic diseases. Few long-term effects of dehydration are discussed here:
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Permanent renal failure can occur due to gradual loss of elasticity of the kidneys.
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Due to deficient oxygen supply to the heart cardiac arrhythmia occurs and can lead to major cardiovascular disorders (myocardial infarctions).
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Permanent damage to Central Nervous System can occur due to cerebral edema (brain swelling) or Cerebral Atrophy (brain shrinkage).
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Osteoporosis and Osteoarthritis due to loss of lubricants in the joints